Canadian Forest Service Publications

Is G1 arrest in plant seeds induced by a p53-related pathway? 2001. Whittle, C.A.; Beardmore, T.; Johnston, M.O. Trends in Plant Science 6: 248-250.

Year: 2001

Issued by: Atlantic Forestry Centre

Catalog ID: 22861

Language: English

CFS Availability: Order paper copy (free)

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Abstract

In mammals, p53 is crucial for inducing the genes that lead to G1 arrest following DNA damage, enabling DNA repair. However, the possibility that such a system exists in plants has attracted little attention. Even though some plan cDNA sequences with partial homology to p53 have been reported recently, there has been little anaysis of how these molecules might relate to DNA damage. The lack of investigation into whether a DNA-damage-induced p53-mediated G1-arrest pathway might exist in plants is remarkable given that plant DNA, like that of all organisms, is continually under the threat of attack.