Canadian Forest Service Publications

Possible function of viroplasm in the replication of eytoplasmic-polyhedrosis virus. 1970. Hayashi, Y.; Kawarabata, T.; Bird, F.T. Pages 105-115 in Proceedings IVth International Colloquium of Insect Pathology. College Park,MD USA. August 1970

Year: 1970

Issued by: Great Lakes Forestry Centre

Catalog ID: 34334

Language: English

Availability: PDF (request by e-mail)

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Newly synthesized CPV-specific RNA and virions are found in a large-granule fraction from infected midguts of Malacosoma disstria which sediments at 10,0000 g and for which the name viroplasm is proposed. The 10,000 g Ppt fraction can synthesize both single and double stranded RNA, as well as virions. A virus-induced RNA polymerase is alson found in association with 10,000 g Ppt fraction but the synthesis of RNA in vitro produces only a single-stranded form. These results suggest that the viroplasm may be the virus-synthesizing factory which has a function not only for virus assembly, but also for synthesis of virus-specific RNA.