Canadian Forest Service Publications

C-methyl flavonols from the fungus Colletotrichum dematium f.sp.epilobii. 1997. Abou-Zaid, M.M.; Dumas, M.T.; Chauret, D.; Watson, A.; Thompson, D.G. Phytochemistry 45(5): 957-961.

Year: 1997

Issued by: Great Lakes Forestry Centre

Catalog ID: 9612

Language: English

Availability: PDF (request by e-mail)

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Two C-6 and C-8 methyl flavonols were isolated from a fungus and identified for the first time. The fungus Colletotrichum dematium f.sp. epilobii is a disease of fireweed, Epilobium angustifolium L ssp. anguslifolium (family Onagraceae): both disease and plant are indigenous to Canada. C. dematium secretes several metabolites when grown in liquid culture. Two novel natural product compounds: 5,4' -dihydroxy-3,7,8 trimethoxy-6-C-methylflavone and 5,4'-dihydroxy-3.6.7-trimethoxy-8-C-methylflavone were isolated form ethyl acetate extracts of liquid culture filtrates. Sturctures were confirmed on the basis of UV'H NMR, CNMR spectroscopy, as well as mass spectroscopic techniques and represent the first report of C-methylflavonols produced by fungi.